Neonatal Outcomes of Twin Pregnancy According to the Planned Mode of Delivery

Schmitz, Thomas MD1,2; Carnavalet, Céline de Carné MD1,2; Azria, Elie MD1,2; Lopez, Emmanuel MD2,3; Cabrol, Dominique MD, PhD1,2; Goffinet, François MD, PhD1,2,4

Obstetrics & Gynecology:
doi: 10.1097/AOG.0b013e318163c435
Original Research
Abstract

OBJECTIVES: To assess neonatal morbidity in twin pregnancy according to the planned mode of delivery.

METHODS: A retrospective cohort study of 758 consecutive sets of twins born after 35 weeks of gestation with a cephalic-presenting first twin was undertaken in a level III maternity unit in which active management of the second twin delivery is performed routinely. The primary outcome was a composite measure of neonatal mortality and morbidity, including pH less than 7.0, 5-minute Apgar score less than 4, neonatal intensive care unit transfer more than 4 days, pneumothorax, and fracture. Control for potential confounders was performed by excluding from the analysis women who experienced pregnancy complications and by using logistic regression models.

RESULTS: Vaginal or cesarean delivery was planned for 657 (86.7%) and 101 (13.3%) women, respectively. Among planned vaginal deliveries, 515 (78.4%) patients delivered both twins vaginally, 139 (21.1%) had a cesarean delivery during labor, and 3 (0.5%) had cesarean delivery for the second twin. After vaginal birth of the first twin, the mean intertwin delivery interval was 4.9±3.2 minutes. When patients who experienced pregnancy complications were excluded (n=202), the neonatal composite morbidity for the second twin did not differ between planned cesarean and planned vaginal delivery (5.0% compared with 4.7%, adjusted odds ratio 1.5, 95% confidence interval 0.3–7.4, P=.63). Neonatal composite morbidity of first twins did not differ between groups.

CONCLUSION: For twin gestations with a cephalic-presenting first twin, planned vaginal delivery after 35 weeks of gestation in selected women remains a safe option in centers used to active management of the second twin delivery.

LEVEL OF EVIDENCE: II

In Brief

Planned vaginal delivery with active management of the second twin after 35 weeks of gestation in selected women remains a safe option.

Author Information

From the 1Maternité Port-Royal, Hôpital Cochin, AP-HP; 2Université Paris Descartes; 3Service de Médecine Néonatale de Port-Royal, Hôpital Cochin, AP-HP; and 4INSERM U149, Hôpital Saint-Vincent-de-Paul, Paris, France.

Corresponding author: Dr. Thomas Schmitz, Maternité Port-Royal, 123 Boulevard de Port-Royal, 75014 Paris, France; e-mail: thomas.schmitz@cch.aphp.fr.

Financial Disclosure The authors have no potential conflicts of interest to disclose.

© 2008 The American College of Obstetricians and Gynecologists