Cost-Effectiveness of Universal Influenza Vaccination in a Pregnant Population

Roberts, Scott MD, MS; Hollier, Lisa M. MD, MPH; Sheffield, Jeanne MD; Laibl, Vanessa MD; Wendel, George D. Jr MD

Obstetrics & Gynecology:
doi: 10.1097/01.AOG.0000210225.45986.99
Original Research
Abstract

OBJECTIVE: The purpose of this study was to estimate whether universal influenza vaccination of pregnant women was cost-effective in the management of influenza-like illness during influenza season.

METHODS: A decision analysis model was developed to investigate the cost-effectiveness of providing inactivated trivalent influenza vaccine to all pregnant women. This scenario was compared with providing supportive care only on a case-by-case basis to the unvaccinated pregnant population.

RESULTS: Vaccination of 100% of pregnant women would save approximately $50 per woman, resulting in a net gain of approximately 45 quality-adjusted hours relative to providing supportive care only.

CONCLUSION: Universal vaccination with inactivated trivalent influenza vaccine is cost-saving relative to providing supportive care alone in the pregnant population.

LEVEL OF EVIDENCE: III

In Brief

For pregnant women, universal vaccination with inactivated trivalent influenza vaccine is more cost-effective than supportive care.

Author Information

From the Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center; and the Department of Obstetrics, Gynecology & Reproductive Sciences, University of Texas Houston Medical School, Dallas, Texas.

See related article on page 1315.

Corresponding author: Scott Roberts, MD, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9032; scott.roberts@utsouthwestern.edu.

© 2006 by The American College of Obstetricians and Gynecologists.