OBJECTIVE: The purpose of this study was to estimate whether universal influenza vaccination of pregnant women was cost-effective in the management of influenza-like illness during influenza season.
METHODS: A decision analysis model was developed to investigate the cost-effectiveness of providing inactivated trivalent influenza vaccine to all pregnant women. This scenario was compared with providing supportive care only on a case-by-case basis to the unvaccinated pregnant population.
RESULTS: Vaccination of 100% of pregnant women would save approximately $50 per woman, resulting in a net gain of approximately 45 quality-adjusted hours relative to providing supportive care only.
CONCLUSION: Universal vaccination with inactivated trivalent influenza vaccine is cost-saving relative to providing supportive care alone in the pregnant population.
LEVEL OF EVIDENCE: III
For pregnant women, universal vaccination with inactivated trivalent influenza vaccine is more cost-effective than supportive care.
From the Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center; and the Department of Obstetrics, Gynecology & Reproductive Sciences, University of Texas Houston Medical School, Dallas, Texas.
See related article on page 1315.
Corresponding author: Scott Roberts, MD, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9032; email@example.com.