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Obstetrics & Gynecology:
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Transurethral Injection of Silicone Microimplants for Intrinsic Urethral Sphincter Deficiency.

KOELBL, HEINZ MD; SAZ, VELI MD; DOERFLER, DANIELA MD; HAEUSLER, GUENTHER MD; SAM, CHRISTINE MD; HANZAL, ENGELBERT MD

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Abstract

Objective: To assess the short-term efficacy of transurethral injection of silicone microimplants in women with intrinsic sphincter deficiency.

Methods: During January 1995 and December 1996, 32 women (mean age 64.3 years, range 39-85 years) with type III stress incontinence (intrinsic sphincter deficiency) underwent transurethral injection of silicone microimplants under general anesthesia. Twenty-eight had undergone previous continence surgery. Subjective and urodynamic assessments were made at 6 and 12 months after injection to evaluate success and short-term effects.

Results: Objective and subjective success rates were 75% and 59% at 6 and 12 months, respectively. Injections of silicone microimplants significantly increased maximum urethral closure pressure (maximum urethral pressure at rest: 34.40 +/- 16.46 cm H2O, 95% confidence interval [CI] 28.55, 40.25 versus 25.35 +/- 10.78 cm H2O, 95% CI 21.52, 29.18; P = .027). There were no complications after surgery up to 1 year.

Conclusion: Transurethral silicone injections were effective in 60% of cases of intrinsic sphincter deficiency, although there was a time-dependent decrease.

(C) 1998 The American College of Obstetricians and Gynecologists

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