Skip Navigation LinksHome > March 1994 - Volume 83 - Issue 3 > Risk Factors for Severe Preeclampsia.
Obstetrics & Gynecology:
Original Article: PDF Only

Risk Factors for Severe Preeclampsia.

STONE, JOANNE L. MD; LOCKWOOD, CHARLES J. MD; BERKOWITZ, GERTRUD S. PhD; ALVAREZ, MANUEL MD; LAPINSKI, ROBERT MD; BERKOWITZ, RICHARD L. MD

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Abstract

Objective: To identify risk factors associated with severe preeclampsia and to determine whether these factors are similar in nulliparous and multiparous patients.

Methods: Patients whose pregnancies were complicated by severe preeclampsia (n=70) were compared retrospectively to 18,964 non-preeclamptic controls. Information on maternal demographic factors; medical, obstetric, and family histories; and neonatal outcome was retrieved and analyzed by univariate and multivariate analysis.

Results: By logistic regression, the only risk factors associated with the development of severe preeclampsia were severe obesity in all patients (adjusted odds ratio 3.5, 95% confidence interval [CI] 1.68-7.46) and a history of preeclampsia in multiparous patients (adjusted odds ratio 7.2, 95% CI 2.74-18.74).

Conclusion: Severe obesity and a history of preeclampsia are the only maternal risk factors identified for the development of severe preeclampsia.

(C) 1994 The American College of Obstetricians and Gynecologists

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