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Familial peripartum cardiomyopathy after molar pregnancy

Massad, L. Stewart MD; Reiss, Craig K. MD; Mutch, David G. MD; Haskel, Ethan J. MD
Obstetrics & Gynecology: May 1993
Article: PDF Only

Background: The potential complications of molar pregnancy are numerous and well defined, but associated peripartum cardiomyopathy has not been reported.

Case: A 16-year-old primigravida with a family history of peripartum cardiomyopathy requiring cardiac transplantation underwent suction curettage of a complete mole at 12 weeks' gestation. Three months after evacuation, she developed congestive heart failure. Radionuclide ventriculography demonstrated an ejection fraction of 30%, echocardiography revealed enlargement and ventricular hypokinesis, and a myocardial biopsy specimen contained hypertrophy and fibrosis without necrosis or active inflammation. The patient improved with medical therapy.

Conclusion: Peripartum cardiomyopathy is a potential complication of molar pregnancy. In spite of the poor prognosis sometimes reported for this disease, good functional outcome may follow. (Obstet Gynecol 1993;81:886–8)

© 1993 The American College of Obstetricians and Gynecologists