Home Articles & Issues Published Ahead-of-Print CME Collections ABOG MOC II Podcasts Videos Journal Info
Skip Navigation LinksHome > July 1988 - Volume 72 - Issue 1 > Primary Invasive Carcinoma of the Vagina
Obstetrics & Gynecology:
Original Article: PDF Only

Primary Invasive Carcinoma of the Vagina

MANETTA, ALBERTO MD; PINTO, JAMES L. MD; LARSON, JAMES E. MD; STEVENS, CLARK W. Jr MD; PINTO, JOANNE S. RN, MSN; PODCZASKI, EDWARD S. MD

Collapse Box

Abstract

A retrospective study of 29 patients with invasive carcinoma of the vagina was completed at The Milton S. Hershey Medical Center, Pennsylvania State University, for a tenyear period from 1976-1986. The overall incidence was 1.3% of all gynecologic malignancies. Twenty-four patients (83%) had squamous cell carcinoma and five (17%) had adenocarcinoma. Squamous cell carcinoma was most commonly located in the upper anterior and lateral vaginal vaults, whereas adenocarcinoma was found more often in the lower anterior and lateral vaginal vaults. The majority of the patients (96%) were managed by a combination of wholepelvis irradiation and brachytherapy. Twenty-four percent of the patients had a recurrence in the vagina only, indicating the need for better local control. The overall survival rate was 48%. Patients with previous hysterectomy were more likely to develop serious treatment-related complications.

(C) 1988 The American College of Obstetricians and Gynecologists

Login

Article Tools

Share