Skip Navigation LinksHome > July 1988 - Volume 72 - Issue 1 > Karyotypes of 1142 Couples With Recurrent Abortion.
Obstetrics & Gynecology:
Original Article: PDF Only

Karyotypes of 1142 Couples With Recurrent Abortion.

PORTNOÏ, MARIE-FRANCE MD; JOYE, NICOLE MD; DEN AKKER, JACQUELINE VAN MD; MORLIER, GENEVIEVE MD; TAILLEMITE, JEAN-LOUIS MD

Collapse Box

Abstract

Cytogenetic analysis was performed on 1142 couples with recurrent pregnancy loss. The frequency of major chromosomal abnormalities per couple was 4.8%. Among 771 couples who had only abortions, the rate of rearrangement did not correlate with the number of abortions. The highest incidence of cytogenetic abnormalities (6.6%) was found in 256 couples with abortion and a normal child. With regard to pregnancy outcome, no unbalanced fetal karyotype was found in prenatal diagnoses, and 40 normal children were born. The risk of unbalanced fetal karyotype is therefore low, but probably high enough for these couples to be offered the possibility of a prenatal diagnosis.

(C) 1988 The American College of Obstetricians and Gynecologists

Login

Article Tools

Share