Exercise is Medicine is a global health initiative of the American College of Sports Medicine. Their goal is to improve the health of every patient through prescriptive exercise, which is a goal-oriented plan for any patient to increase physical exercise. The gastrointestinal nurse works in various settings with a variety of patients who have numerous chief complaints that can be helped by prescriptive exercise. Resources the patient, nurse, and provider can use to help patients reach their exercise goals are discussed. The amount of time required for these activities is minimal and can be accomplished by the gastrointestinal nurse and provider in 15–20 seconds during a normal office visit.