Skip Navigation LinksHome > May/June 2007 - Volume 30 - Issue 3 > Moderate Dietary Temperance Effectively Prevents Relapse of...
Gastroenterology Nursing:
doi: 10.1097/01.SGA.0000278169.35930.f8
Feature

Moderate Dietary Temperance Effectively Prevents Relapse of Crohn Disease: A Prospective Study of Patients in Remission

Tanaka, Makoto PhD, RN, PHN; Iwao, Yasushi PhD, MD; Sasaki, Satoshi PhD, MD; Okamoto, Susumu PhD, MD; Ogata, Haruhiko PhD, MD; Hibi, Toshifumi PhD, MD; Kazuma, Keiko PhD, RN, PHN

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Abstract

The authors examined the influence of diet (dietary fat intake and dietary temperance) on relapse of patients with Crohn disease. A 1-year prospective study of 76 patients with Crohn disease was conducted. The criterion for eligibility was a Crohn Disease Activity Index score of 150 or lower for at least 1 month. The primary end point was defined as the relapse-free interval from the baseline until the first relapse. Fat intake was assessed using a validated diet history questionnaire. The degree of dietary temperance was assessed using a single-item nominal scale. The Cox proportional hazards model was used to evaluate the influence of diet. Crohn disease relapse was seen in 25 patients (33%), and 47 patients (62%) remained in continuous remission. A decreased ratio of n-6 polyunsaturated fatty acid (PUFA) to n-3PUFA (odds ratio = .38; p = .005) was associated with a poor prognosis. Dietary temperance also was significantly associated with prognosis (p = .014). More moderate dietary temperance decreased the risk of relapse (odds ratio = .22; p = .006). Effective prevention of relapse for Crohn disease patients might be achieved through moderate dietary temperance, particularly when the disease condition is unstable.

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