Endoscopic ultrasonography-guided fine-needle aspiration cytology (EUS-FNA) may provide full-thickness biopsies, adequate for cytology and histology. In the present case report, we describe the first cases of a rare well-differentiated squamous esophageal carcinoma (verrucous esophageal cancer), finally diagnosed by EUS-FNA using a large FNA needle after several upper endoscopies with biopsies negative for malignancy. In this report, we highlight the usefulness of this procedure and EUS features in the diagnosis of suspicious esophageal lesions with negative endoscopic biopsies for malignancy.
Departments of aGastroenterology
bPathology, Endoscopy Unit, University Hospital of Canary Islands, Tenerife, Spain
cDepartment of Internal Medicine, Gastroenterology Unit, Alhossien Hospital, Alazhar University, Cairo, Egypt
dDepartment of Gastroenterology
eDepartment of Pathology, Saint Luc University Hospital, Montreal, Quebec, Canada
*Zaida Adrián-de-Ganzo and Antonio Z. Gimeno-García contributed equally to the writing of this article.
Correspondence to Antonio Z. Gimeno-García, MD, Department of Gastroenterology, Endoscopy Unit, University Hospital of Canary Islands, Ofra s/n.38320, La Laguna, Tenerife, Spain Tel/fax: +34 922 678 554; e-mail: email@example.com
Received April 22, 2013
Accepted June 13, 2013