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Six clinical cases of Mandragora autumnalis poisoning: diagnosis and treatment

Piccillo, Giovita A.a; Mondati, Enrico G.M.a; Moro, Paola A.b

European Journal of Emergency Medicine: December 2002 - Volume 9 - Issue 4 - pp 342-347
Case Reports

A multiple case of Mandragora autumnalis poisoning is described. Mandragora autumnalis, a solanaceous plant that is common in the Sicilian countryside, contains a variable concentration of solanum alkaloids, which cause gastrointestinal irritation, and tropane alkaloids, which have anticholinergic properties and produce typical and sometimes severe atropine-like symptoms. Vital function support, decontamination, symptomatic treatment and, in severe cases, antidote therapy with physostigmine are useful to control acute poisoning.

aDepartment of Internal and Emergency Medicine, University of Catania, St Marta Hospital, Catania, Italy

bPoison Control Centre of Milan, Milan, Italy

Correspondence to G.A. Piccillo, Department of Internal and Emergency Medicine, University of Catania, St Marta Hospital, via G. Clementi 36, 95124 Catania, Italy

© 2002 Lippincott Williams & Wilkins, Inc.