Abstracts: ISEE 21st Annual Conference, Dublin, Ireland, August 25-29, 2009: Symposium Abstracts
Background and Objective:
Long-term exposure to road traffic and aircraft noise has been reported to be associated with increased risk of myocardial infarction and hypertension. Road traffic is the main source of both noise and air pollution. Air pollution has also been linked to cardiovascular morbidity and mortality. So far, the knowledge about the relative importance of these traffic-related exposures for developing cardiovascular diseases is rather limited.
The aim of the project is to study the association between residential transport-related noise and the risk of cardiovascular morbidity and mortality by simultaneously controlling for residential nitrogen dioxide (NO2) as indicator of traffic-related air pollution. This presentation will describe the project design, with focus on exposure assessment.
A population-based cross-sectional study “The Oslo Health Study” (HUBRO) was performed in 2000–2001. About 46% (N = 18,770) of the invited subjects answered a questionnaire and underwent a physical examination. Blood pressure, serum total cholesterol, serum HDL cholesterol and serum triglycerides were measured. In 2009 “The Oslo Health and Environment study” will send a questionnaire to the population invited to HUBRO that lives in Oslo in 2009 (N = 28,000). This follow-up study will collect information on noise annoyance, noise sensitivity, sleep disturbances and bedroom orientation along with self-reported cardiovascular diseases, symptoms and potential confounders. The data will be linked to different health registries including the Death registry of Norway.
Transport-related noise will be assessed for each participant’s home addresses during 1992–2006. The noise indicator Lden (day-evening-night) will be calculated outside the most exposed façade and Lnight will be assessed outside the bedroom façade of each house using a Geographical Information System model. NO2 will be assessed using the EPISODE dispersion model for the same addresses and time period.