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Park, M*; Park, S*; Hong, Y*; Chung, H†; Kim, H*
*Seoul National University, South Korea; and †Sung Kyun Kwan University, South Korea.
Ambient particulate pollutants have been reported to affect mortality and morbidity of respiratory disease. However, factors influencing the relationship between particulate pollutants and asthma have not been evaluated well. We investigated factors affecting hospital visits for asthma in relation to PM10 exposure.
To evaluate the risk of PM10-associated hospital visits for asthma, we used a time-series study design. We calculated the risk for an interquartile increase of PM10 in 6 major cities during a 6-year period in Korea. Factors influencing the risk were evaluated by metaregression analysis on the risk estimates of the 6 cities with population density, ambient temperature, number of vehicles, and mean concentration of PM10 of the cities.
Odds ratio of hospital visits for asthma by interquartile increase of PM10 was 1.008 for people aged 30 to 64 years and 1.025 for the elderly (≥65 years). From the metaregression analysis, we found population density, ambient temperature, and number of vehicles influence the PM10-associated hospital visits for asthma in the younger age group while these factors did not significantly affect the risk in the elderly people.
Ambient particulate pollutants (PM10) significantly increased the risk of hospital visits for asthma and the elderly were more susceptible than the younger people. Factors affecting the risk of PM10-associated hospital visits for asthma were different between the 2 age groups.
© 2007 Lippincott Williams & Wilkins, Inc.
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