Skip Navigation LinksHome > November 2010 - Volume 21 - Issue 6 > Breast-feeding and Childhood Hospitalizations for Infections
doi: 10.1097/EDE.0b013e3181f55803
Infectious Disease: Original Article

Breast-feeding and Childhood Hospitalizations for Infections

Tarrant, Mariea; Kwok, Man-Kib; Lam, Tai-Hingb; Leung, Gabriel M.b; Schooling, C. Maryb

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Background: Infectious disease is a leading cause of morbidity and hospitalization for infants and children. During infancy, breast-feeding protects against infectious diseases, particularly respiratory infections, gastrointestinal infections, and otitis media. Little is known about the longer-term impact of breast-feeding on infectious disease in children.

Methods: We investigated the relationship between infant feeding and childhood hospitalizations from respiratory and gastrointestinal infections in a population-based birth cohort of 8327 children born in 1997 and followed for 8 years. The main outcomes were public hospital admissions for respiratory infections, gastrointestinal infections, and all infectious diseases. Cox regression was used to assess time to first hospitalization.

Results: Breast-feeding only (no formula-feeding) for 3 or more months was associated with a lower risk of hospital admission in the first 6 months of life for respiratory infections (hazard ratio = 0.64 [95% confidence interval = 0.42–0.97]), gastrointestinal infections (0.51 [0.25–1.05]), and any infection (0.61 [0.44–0.85]), adjusted for sex, type of hospital at birth, and household income. Partial breast-feeding (both breast-feeding and formula-feeding) in the first 3 months also reduced hospitalizations from infections but with smaller effect sizes. Beyond 6 months of age, there was no association between breast-feeding status at 3 months and hospitalization for infectious disease.

Conclusions: Giving breast milk and no formula for at least 3 months substantially reduced hospital admissions for many infectious diseases in the first 6 months of life, when children are most vulnerable.

© 2010 Lippincott Williams & Wilkins, Inc.

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