Background and objective: This prospective, clinical pilot trial compared the Short Form 36 Health Survey (SF-36) and a nine-item quality of recovery [Quality of Recovery 9 (QoR-9)] survey to assess the 1-week outcome after liver resection and prediction of postoperative complications from baseline values before liver resection.
Methods: In 19 patients, the SF-36 was recorded preoperatively (baseline) and on postoperative day (POD) 7. SF-36 z-values (means ± SD) for the physical component summary (PCS) and mental component summary (MCS) were calculated. QoR-9 (score 0–18) was performed at baseline, POD1, POD3, POD5 and POD7. Descriptive analysis and effect sizes (d) were calculated.
Results: From baseline to POD7, PCS decreased from −0.38 ± 1.30 to −2.10 ± 0.76 (P = 0.002, d = −1.57) and MCS from −0.71 ± 1.50 to −1.33 ± 1.11 (P = 0.061, d = −0.46). QoR-9 was significantly lower at POD1, POD3 and POD5 compared with baseline (P < 0.050, d < −2.0), but not at POD7 (P = 0.060, d = −1.08). Baseline PCS was significantly lower with a high effect size in patients with complications (n = 12) compared with patients without complications (n = 7) (−0.76 ± 1.46 vs. 0.27 ± 0.56; P = 0.044, d = −0.84) but not baseline MCS (P = 0.831, d = −0.10) or baseline QoR-9 (P = 0.384, d = −0.44).
Conclusions: The SF-36 indicates that liver resection surgery has a higher impact on physical health than on mental health. QoR-9 determines the feasible time course of recovery with a 1-week return to baseline. Preoperative impaired physical health might predict postoperative complications.
aUniversity Department of Anaesthesiology and Pain Therapy, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
bDepartment of Anaesthesiology and Intensive Care Medicine, Donauspital, Vienna, Austria
cUniversity Department of Visceral and Transplantation Surgery, Inselspital, Switzerland
dUniversity Department of Intensive Care Medicine, Bern University Hospital, University of Bern, Bern, Switzerland
eInstitute of Medical Biometry, Epidemiology and Informatics, Johannes Gutenberg-University Mainz, Mainz, Germany
Received 8 September, 2008
Revised 24 November, 2008
Accepted 27 December, 2008
Correspondence to Andreas Vogt, University Department of Anaesthesiology and Pain Therapy, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland Tel: +41 31 632 42 17; fax: +41 31 632 05 54; e-mail: firstname.lastname@example.org
The data were presented in part at the European Society of Anaesthesiology annual meeting, 2007.