Skip Navigation LinksHome > December 2012 - Volume 28 - Issue 4 > Electroconvulsive Therapy in an Adolescent With Autism and B...
Journal of ECT:
doi: 10.1097/YCT.0b013e31825cec86
Case Reports

Electroconvulsive Therapy in an Adolescent With Autism and Bipolar I Disorder

Siegel, Matthew MD*; Milligan, Briana BA*; Robbins, Douglas MD; Prentice, Glenn MD

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Objectives: We report a positive response to electroconvulsive therapy in a severely functionally impaired adolescent with autistic disorder and classic bipolar I disorder, including an episodic pattern of decreased need for sleep, hypersexuality, expansive and agitated affect, aggression, self-injury, and property destruction.

Methods: After ineffective trials of mood stabilizers and antipsychotics as well as inability to sustain a positive response to lithium due to medication noncompliance, a course of acute and maintenance electroconvulsive therapy was attempted.

Results: A marked and sustained improvement across all symptom categories, as measured by directly observed frequency counts of target behaviors in an inpatient setting, was obtained.

Conclusions: Electroconvulsive therapy should be considered a potentially useful intervention in cases of children with autistic disorder and a severe comorbid affective disorder.

© 2012 Lippincott Williams & Wilkins, Inc.


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