The Journal of ECT

Skip Navigation LinksHome > September 2012 - Volume 28 - Issue 3 > Methohexital and Succinylcholine Dosing for Electroconvulsiv...
Journal of ECT:
doi: 10.1097/YCT.0b013e3182503bc9
Online Articles

Methohexital and Succinylcholine Dosing for Electroconvulsive Therapy (ECT): Actual Versus Ideal

Bryson, Ethan O. MD*†; Aloysi, Amy S. MD; Popeo, Dennis M. MD; Bodian, Carol A. DrPH*; Pasculli, Rosa M. BA; Briggs, Mimi C. BA; Kellner, Charles H. MD

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Abstract: This report compares the actual doses of methohexital and succinylcholine used for optimal anesthesia and muscle relaxation in electroconvulsive therapy with written guidelines for dosing. The initial doses of methohexital and succinylcholine in milligrams per kilogram were reviewed and compared with subsequent doses of each agent after adjustments were made for individual patient responses during treatment. The dose of methohexital required to induce general anesthesia for most patients is 1.0 mg/kg. The dose of succinylcholine required to provide adequate muscle relaxation during electroconvulsive therapy is 0.9 mg/kg, although there is considerable variability in patient response to this drug.

© 2012 by Lippincott Williams & Wilkins


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