The Journal of ECT

Skip Navigation LinksHome > September 2010 - Volume 26 - Issue 3 > Electroconvulsive Therapy-Responsive Catatonia in a Medicall...
Journal of ECT:
doi: 10.1097/YCT.0b013e3181c18a8c
Case Reports

Electroconvulsive Therapy-Responsive Catatonia in a Medically Complicated Patient

Romanowicz, Magdalena MD; Sola, Christopher L. DO

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Background: Profoundly depressed states of awareness classified as either catatonia or akinetic mutism have been reported in patients with various general medical conditions including encephalitis, frontal lobe tumors, or paraneoplastic limbic encephalitis. Catatonic features are often difficult to apprise in this context. This can result in electroconvulsive therapy (ECT) discontinuation, although it remains the most effective treatment of catatonia.

Case Report: We describe the case of a patient with a history of unresectable right retroorbital squamous cell carcinoma, status poststereotactic radiation and cisplatin, and subsequent pneumococcal meningitis of the temporal lobe with abscess formation who became catatonic after receiving 3 bitemporal treatments with ECT for severe depression and whose catatonia improved with continued ECT. Furthermore, she demonstrated progressive improvement in mood, interactivity, and overall neurologic function after ECT treatment was completed.

Conclusions: The search for an etiology of a profound catatonic state should include the probability of underlying medical disorder. Although lorazepam may be helpful in some cases, ECT deserves early consideration in catatonia, especially in cases where the underlying cause seems to be uncertain, even if the catatonia begins in the midst of treatment.

© 2010 Lippincott Williams & Wilkins, Inc.


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