We report a case of a patient with Fahr disease affected by bipolar disorder type I with psychotic symptoms. The complex clinical picture, characterized by both neurological and psychiatric symptoms, proved to be partially or completely resistant to several pharmacological trials. On the contrary, a marked improvement of clinical picture occurred after a cycle of 10 sessions of electroconvulsive therapy, followed by a complete and sustained resolution of mood, cognitive, motor, and behavioral symptoms during the next 4 years.
From the *Division of Psychiatry, University of Pisa, Pisa, Italy; †Department of Psychiatry, Massachusetts General Hospital; and ‡Department of Psychiatry, Harvard Medical School, Boston, MA.
Received in October 7, 2008; Accepted for publication October 10, 2008.
Reprints: Francesco Casamassima, MD, Dipartimento di Psichiatria, University of Pisa, Via Roma, 67, 56100 Pisa, Italy (e-mail: firstname.lastname@example.org, email@example.com).