Ear and Hearing

Skip Navigation LinksHome > March/April 2014 - Volume 35 - Issue 2 > Sample Size Requirements for Establishing Clinical Test–Rete...
Ear & Hearing:
doi: 10.1097/01.aud.0000438377.15003.6b
Brief Report

Sample Size Requirements for Establishing Clinical Test–Retest Standards

McMillan, Garnett P.1,2; Hanson, Timothy E.3

Collapse Box


Objective: To define sample size requirements for establishing clinical serial monitoring protocols.

Design: The 95% confidence bound of a critical difference score is defined and used to identify false-negative regions suitable for sample size calculation.

Results: Reference subject sample sizes vary from about 40 to 480 subjects, depending on the minimum acceptable error rates of the clinical protocol.

Conclusions: Sample size requirements for establishing test–retest standards are generally defined and suitable for any serial monitoring protocol.

© 2014 by Lippincott Williams & Wilkins


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.