Assessment of stress distribution on bone with a combination of two different dental implant materials and three different crown materials was performed in this study. A three-dimensional finite element model was constructed by a commercial finite element package. Three different crown materials (E-Max, gold alloy, zirconium core) were investigated. In addition, two different implant materials (titanium–zirconium) were tested simultaneously in six case studies. According to the finite element analysis results, changing crown materials showed different behaviors of stresses and deformation values on cortical and spongy bones, similar to changing implant materials. Linear static analysis results showed similar distributions, and safe values of stresses and deformations, that were generated on all parts of the studied system. Using crown materials with lower modulus of elasticity reduced the stresses generated on the jaw bone (cortical and spongy), it absorbed more energy from the applied load, and transferred less energy to the following parts of the system (implant–abutment complex and bones). However, using more rigid material for implant may be preferred for weak bones in terms of absorbing the applied load energy and transferring less deformation to the underlying structures.