Orbital floor fractures account for the majority of all traumas involving the middle third of the face. The aim of the treatment in those patients is to free orbital contents, restore floor continuity, and minimize soft tissue fibrosis. Different materials have been tested over the years; however, none of those materials fulfil the ideal requirements of the graft, which necessitates continuous search for a new material. Bovine collagen membrane has been successfully used in oral surgery and wound care. The present study was designed to investigate the use of collagen membrane in the treatment of orbital floor fracture.