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Daily Use of a Facial Broad Spectrum Sunscreen Over One-Year Significantly Improves Clinical Evaluation of Photoaging

Randhawa, Manpreet PhD; Wang, Steven MD; Leyden, James J. MD; Cula, Gabriela O. PhD; Pagnoni, Alessandra MD; Southall, Michael D. PhD

doi: 10.1097/DSS.0000000000000879
Original Article

BACKGROUND: Sunscreens are known to protect from sun damage; however, their effects on the reversal of photodamage have been minimally investigated.

OBJECTIVE: The aim of the prospective study was to evaluate the efficacy of a facial sun protection factor (SPF) 30 formulation for the improvement of photodamage during a 1-year use.

METHODS: Thirty-two subjects applied a broad spectrum photostable sunscreen (SPF 30) for 52 weeks to the entire face. Assessments were conducted through dermatologist evaluations and subjects' self-assessment at baseline and then at Weeks 12, 24, 36, and 52.

RESULTS: Clinical evaluations showed that all photoaging parameters improved significantly from baseline as early as Week 12 and the amelioration continued until Week 52. Skin texture, clarity, and mottled and discrete pigmentation were the most improved parameters by the end of the study (40% to 52% improvement from baseline), with 100% of subjects showing improvement in skin clarity and texture.

CONCLUSION: The daily use of a facial broad-spectrum photostable sunscreen may visibly reverse the signs of existing photodamage, in addition to preventing additional sun damage.

*Skin Research Center, Johnson & Johnson Consumer Companies, Inc., Skillman, New Jersey;

Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, New York;

KGL Skin Study Center, Broomall, Pennsylvania;

§Pagnoni Consulting LLC

Address correspondence and reprint requests to: Manpreet Randhawa, PhD, Skin Research Center, Johnson & Johnson Consumer Companies, Inc., 199 Grandview Road, Skillman, NJ 08558, or e-mail: MRandha1@its.jnj.com

The investigation was approved by an institutional review board. This research was supported and funded by Johnson & Johnson Consumer Companies Inc. M. Randhawa, G.O. Cula, and M. Southall are employees of Johnson & Johnson Consumer Companies, Inc., the manufacturer of the formulation tested. J.J. Leyden is an employee of KGL Laboratories, the independent testing laboratory that received compensation for conducting this study, and is an investigator for this study. S. Wang is a consultant for Johnson & Johnson Consumer Companies. Writing and editorial assistance was provided by A. Pagnoni, MD of Pagnoni Consulting LLC. A. Pagnoni is consultant for Johnson & Johnson Consumer Companies, Inc.

© 2016 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
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