Skip Navigation LinksHome > March/April 2013 - Volume 24 - Issue 2 > Contact Sensitization to Modern Wound Dressings in 70 Patien...
doi: 10.1097/DER.0b013e318284d9f2

Contact Sensitization to Modern Wound Dressings in 70 Patients With Chronic Leg Ulcers

Renner, Regina MD*†; Simon, Jan C. MD*; Treudler, Regina MD*

Collapse Box


Background: Patients with chronic leg ulcers typically experience contact allergy to topical treatments. Although declared as hypoallergenic, modern wound dressings have caused several reported cases of contact allergy.

Objective: The aim of the study was to evaluate any allergenic potential of modern wound dressings in patients with leg ulcers.

Methods: Seventy-one patients were included in our prospective observation. Patch tests were performed with a selection of 10 modern wound dressings and with selected allergens according to series of the German Contact Dermatitis Research Group (DKG).

Results: Of 70 patients eligible for evaluation, 12 (17%) were positive for the hydrogel NuGel, followed by the hydrocolloid NuDerm (n = 7/70, 10%) and the ionic silver−containing wound dressing Aquacel Ag and the gauze Adaptic (both n = 4/70, 5%). Patients with recalcitrant ulcers of prolonged duration showed a significant higher number of epicutaneous sensitizations to wound dressings than patients with shorter ulcer duration.

Conclusions: The allergenic potential of modern wound dressings should not be underestimated. There is need for precise declaration of all ingredients.

© 2013 American Contact Dermatitis Society

You currently do not have access to this article.

You may need to:

Note: If your society membership provides for full-access to this article, you may need to login on your society’s web site first.


Article Tools


Article Level Metrics