Skip Navigation LinksHome > July 2014 - Volume 57 - Issue 7 > Laparoscopic Colorectal Resections: A Simple Predictor Mode...
Diseases of the Colon & Rectum:
doi: 10.1097/DCR.0000000000000137
Original Contributions: Benign Colorectal Disease

Laparoscopic Colorectal Resections: A Simple Predictor Model and a Stratification Risk for Conversion to Open Surgery

Vaccaro, Carlos A. M.D., Ph.D.1; Rossi, Gustavo L. M.D.1; Quintana, Guillermo Ojea M.D.1; Soriano, Enrique R. M.D., M.S.C.2; Vaccarezza, Hernan M.D.1; Rubinstein, Fernando M.D, M.P.H.3

Supplemental Author Material
Collapse Box

Abstract

BACKGROUND: The advantages associated with the laparoscopic approach are lost when conversion is required. Available predictive models have failed to show external validation. Body surface area is a recently described risk factor not included in these models.

OBJECTIVE: The aim of this study was to develop a clinical rule including body surface area for predicting conversion in patients undergoing elective laparoscopic colorectal surgery.

DESIGN: This was a prospective cohort study.

SETTING: This study was conducted at a single large tertiary care institution.

PATIENTS: Nine hundred sixteen patients (mean age, 63.9; range, 14–91 years; 53.2% female) who underwent surgery between January 2004 and August 2011 were identified from a prospective database.

MAIN OUTCOME MEASURES: Conversion rate was analyzed related to age, sex, obesity, disease location (colon vs rectum), type of disease (neoplastic vs nonneoplastic), history of previous surgery, and body surface area. A predictive model for conversion was developed with the use of logistic regression to identify independently associated variables, and a simple clinical prediction rule was derived. Internal validation of the model was performed by using bootstrapping.

RESULTS: The conversion rate was 9.9% (91/916). Rectal disease, large patient size, and male sex were independently associated with higher odds of conversion (OR, 2.28 95%CI, 1.47–3.46]), 1.88 [1.1–3.44], and 1.87 [1.04–3.24]). The prediction rule identified 3 risk groups: low risk (women and nonlarge males), average risk (large males with colon disease), and high risk (large males with rectal disease). Conversion rates among these groups were 5.7%, 11.3%, and 27.8% (p < 0.001). Compared with the low-risk group, ORs for average- and high-risk groups were 2.17 (1.30–3.62, p = 0.004) and 6.38 (3.57–11.4, p < 0.0001).

LIMITATIONS: The study was limited by the lack of external validation.

CONCLUSION: This predictive model, including body surface area, stratifies patients with different conversion risks and may help to inform patients, to select cases in the early learning curve, and to evaluate the standard of care. However, this prediction rule needs to be externally validated in other samples (see Video, Supplemental Digital Content 1, http://links.lww.com/DCR/A137).

© 2014 The American Society of Colon and Rectal Surgeons

Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.