PURPOSE: This study aimed to assess the safety and efficacy of a novel colostomy continence device.
METHODS: This phase II, 142-day, open-label, nonrandomized, multicenter study enrolled patients who had end colostomies for ≥3 months. Study stages were usual pouching (21 days), wafer transition (14 days), and the device (107 days). During device wear, up to 8 hours per day, patients recorded the following outcomes in daily diaries: skin condition (if the wafer was changed); stoma color, moisture, and physical condition; and gastrointestinal symptoms.
RESULTS: Of the 26 patients enrolled, 25 wore at least one device. The device was worn on 96% of study days and a mean of 6.8 hours per day. Adverse events were reported by 1 patient during the usual pouching 21-day period, by 5 patients during the wafer transition 14-day period, and by 15 patients during the device wear 107-day period. Stoma color and moisture were within normal range on all daily assessments. The device did not affect microbiology or vascularity. During device wear, patients had no unusual gastrointestinal symptoms or odor on >99% and 80% of days, respectively. The mean number of leaks per patient-month was 1.2 with usual pouching, 4.2 with the device overall, and 2.1 during the last 3 weeks with the device, suggesting a learning curve. Approximately 65% of patients preferred the device to usual pouching at the end of study.
CONCLUSIONS: The novel continence device was safe and effective for up to 8 hours per day in colostomy patients.
1 Image Specialties, St. Joseph, Missouri
2 Colon and Rectal Surgery Inc., Columbus, Ohio
3 Carondelet St. Mary's Hospital and Health Center, Tucson, Arizona
4 Restored Images, Kansas City, Missouri
5 ConvaTec Inc., Skillman, New Jersey
Funding: This work was supported by ConvaTec Inc. The sponsor designed the study and reviewed and approved the final manuscript; the authors had full control over the contents of the manuscript and approved the final submission.
Financial Disclosure: Dr Kommala is an employee of ConvaTec Inc. The other authors report no conflicts of interest and received no financial support to write the manuscript.
This study was registered with ClinicalTrials.gov (NCT00809406).
Presented at the meeting of The American Society of Colon and Rectal Surgeons, Hollywood, FL, May 2 to 6, 2009.
Correspondence: Terri Maxwell, M.S.N., F.N.P., Image Specialties, 3410 Ashland Ave, St. Joseph, MO 64506. E-mail: email@example.com