You could be reading the full-text of this article now if you...

If you have access to this article through your institution,
you can view this article in

Adenocarcinoma Arising in the Middle of Ileoanal Pouches: Report of Five Cases.

Ault, Glenn T. M.D.; Nunoo-Mensah, Joseph W. M.D., F.R.C.S.(Engl.); Johnson, Laura M.D.; Vukasin, Petar M.D.; Kaiser, Andreas M.D.; Beart, Robert W. Jr. M.D.

Diseases of the Colon & Rectum:
doi: 10.1007/DCR.0b013e318199effe
Case Reports
Abstract

Restorative proctocolectomy with ileal pouch-anal anastomosis with or without mucosectomy has become the procedure of choice in patients with long-standing ulcerative colitis complicated by malignancy or medically refractory disease and for familial polyposis syndrome. Some reports have demonstrated the development of malignancy at the ileoanal anastomosis. We present a recent series of five patients who developed adenocarcinoma in the middle of their ileal pouch including the first case of pouch carcinoma in a patient who underwent pouch formation for ulcerative colitis. We discuss their presentation and management. Development of ileal pouch cancers, while rare, has been seen with increasing frequency in our practice. Patients with long-standing ileal pouches may benefit from routine surveillance of the pouch as often as every six months, which can be performed quickly and easily in the office using flexible endoscopy.

Author Information

Department of Colorectal Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California

Address of correspondence: Glenn Ault, M.D., Department of Colorectal Surgery, University of Southern California, 1441 Eastlake Avenue, Suite 7418, Los Angeles, California 90033. E-mail: ault@usc.edu

© The ASCRS 2009