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Coronary Artery Disease:
doi: 10.1097/MCA.0000000000000105
Original Research

Preprocedural red blood cell distribution width predicts bare metal stent restenosis

Yildiz, Abdulmelika; Tekiner, Fatiha; Karakurt, Ahmetc; Sirin, Gokcea; Duman, Dursunb

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Abstract

Background

It has been shown that increased red blood cell distribution width (RDW) predicts adverse outcomes in cardiovascular disease and in patients undergoing a percutaneous coronary intervention. The aim of the present study was to assess the predictive value of preinterventional RDW on the development of in-stent restenosis (ISR) in patients undergoing stent implantation.

Materials and methods

In this retrospective study, we compared 131 patients with ISR and 138 patients without ISR who had undergone bare metal stent implantation.

Results

Preprocedural RDW was significantly higher in patients with ISR than those without restenosis (14.6±3.2 vs. 13.4±1.6%, P<0.001). Stent length was significantly longer in patients with than those without restenosis (17.9±5.6 vs. 16.2±5.2 mm, respectively, P=0.03). Compared with patients with restenosis, patients without restenosis had a lower rate of diabetes (28 vs. 61 patients, P=0.001), a significantly short period between two coronary angiographies (9.8±9.3 vs. 12.9±11.6 months, respectively, P=0.02), and lower triglyceride levels (133±53 vs. 198±121 mg/dl, respectively, P=0.05). In multivariate logistic regression analysis, diabetes mellitus, stent length, preprocedural RDW, and current smoking independently predicted ISR.

Conclusion

Increased preinterventional RDW significantly predicts bare metal stent restenosis and might represent a useful screening tool to stratify patients according to a higher or a lower risk of ISR after stent implantation in patients with stable and unstable angina pectoris.

© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins

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