Skip Navigation LinksHome > August 2014 - Volume 25 - Issue 5 > Can the T-peak to T-end interval be a predictor of mortality...
Coronary Artery Disease:
doi: 10.1097/MCA.0000000000000101
Original Research

Can the T-peak to T-end interval be a predictor of mortality in patients with ST-elevation myocardial infarction?

Tatlisu, Mustafa A.; Özcan, Kazim S.; Güngör, Bariş; Ekmekçi, Ahmet; Çekirdekçi, Elif İ.; Aruğarslan, Emre; Çinar, Tufan; Zengin, Ahmet; Karaca, Mehmet; Eren, Mehmet; Erdinler, İzzet

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Abstract

Background

The interval between the peak and the end of the T wave (Tp–e interval) on 12-lead ECG is a measure of transmural dispersion of repolarization and may be related to malignant ventricular arrhythmias. The objective of this study was to investigate whether the Tp–e interval predicts in-hospital and long-term mortality in patients with ST-segment elevation myocardial infarction (STEMI) undergoing a primary percutaneous coronary intervention (pPCI).

Methods

This study included 488 consecutive patients with STEMI treated with pPCI. Electrocardiograms were obtained after pPCI and the Tp–e interval was measured in leads without ST-segment elevation.

Results

There were 46 (9.4%) deaths in the population, with a mean follow-up time of 21.1±10.2 months. The Tp–e interval was associated with not only in-hospital ventricular tachycardia/fibrillation, target vessel revascularization, and death but also long-term target vessel revascularization and death. Furthermore, the Tp–e interval measured using the tail method was found to be a significant predictor of long-term mortality in multivariable Cox analyses [odds ratio 1.018, 95% confidence interval (1.004–1.033)]. Findings were similar in the Tp–e interval and the heart rate-corrected Tp–e interval (cTp–e).

Conclusion

Tp–e and cTp–e measured using the tail method were found to be predictors of both in-hospital and long-term mortality.

© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins

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