Skip Navigation LinksHome > Published Ahead-of-Print > Treatments for Corneal Neovascularization: A Review.
doi: 10.1097/01.ico.0000396158.53170.1f
Review: PDF Only

Treatments for Corneal Neovascularization: A Review.

Gupta, Deepak MRCOphth; Illingworth, Chris MD, FRCS

Published Ahead-of-Print
Collapse Box


Corneal neovascularization (CNV) may be a physiological response to various stimuli, but a chronic and persistent upregulation of neoangiogenesis can result in pathological CNV. Pathological blood vessels are immature and lack structural integrity, predisposing the cornea to lipid exudation, inflammation, and scarring. CNV can therefore become a potentially blinding condition. In this review, we frame CNV in an epidemiological perspective, consider risk factors for CNV, provide an overview of CNV pathogenesis, and consider the impact of CNV on corneal transplantation. We consider treatments that are of largely historical interest, before reviewing contemporary medical and surgical treatments. Within medical treatments, we report on steroids, nonsteroidal anti-inflammatory agents, antivascular endothelial growth factor agents, and cyclosporine. Within surgical treatments, we report on the use of lasers, photodynamic therapy, superficial keratectomy, and diathermy/cautery-based treatments.

Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.