Skip Navigation LinksHome > September 2014 - Volume 33 - Issue 9 > Mitomycin-C for Mucous Membrane Overgrowth in OOKP Eyes
doi: 10.1097/ICO.0000000000000183
Case Report

Mitomycin-C for Mucous Membrane Overgrowth in OOKP Eyes

Avadhanam, Venkata S. MS, FRCS, FRCOphth*,†; Herold, Jim FDRCS (Eng), FRCS (Ed), FRCS (Eng); Thorp, Simon MBChB, DA, MRCA, FCARCSI, FFPMCAI; Liu, Christopher S. C. FRCOphth*,†,§

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Purpose: The aim of this study was to report the use of mitomycin-C (MMC) in the treatment of mucous membrane overgrowth in eyes with osteo-odonto-keratoprosthesis (OOKP).

Methods: Records of 4 cases with mucous membrane overgrowth after stage 2 OOKP surgery were reviewed.

Results: All the patients had undergone a mucous membrane trimming procedure followed by MMC application. None of the patients had any episode of recurrence of the mucous membrane overgrowth after a single application of MMC in the follow-up period that ranged from 1 to 11 years.

Conclusions: MMC can successfully arrest mucous membrane overgrowth in OOKP-implanted eyes including refractory cases.

© 2014 by Lippincott Williams & Wilkins.


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