Purpose: The aim of this study was to report the use of mitomycin-C (MMC) in the treatment of mucous membrane overgrowth in eyes with osteo-odonto-keratoprosthesis (OOKP).
Methods: Records of 4 cases with mucous membrane overgrowth after stage 2 OOKP surgery were reviewed.
Results: All the patients had undergone a mucous membrane trimming procedure followed by MMC application. None of the patients had any episode of recurrence of the mucous membrane overgrowth after a single application of MMC in the follow-up period that ranged from 1 to 11 years.
Conclusions: MMC can successfully arrest mucous membrane overgrowth in OOKP-implanted eyes including refractory cases.
*Sussex Eye Hospital, Brighton, United Kingdom;
†Brighton and Sussex Medical School, Brighton, United Kingdom;
‡Royal Sussex County Hospital, Brighton, United Kingdom; and
§Tongdean Eye Clinic, Hove, United Kingdom.
Reprints: Christopher S. C. Liu, FRCOphth, Sussex Eye Hospital, Eastern Road, Brighton BN2 5BF, United Kingdom (e-mail: firstname.lastname@example.org).
The authors have no funding or conflicts of interest to disclose.
Received September 02, 2013
Accepted May 09, 2014