Skip Navigation LinksHome > September 2014 - Volume 33 - Issue 9 > Herpes Zoster Stromal Keratitis After Varicella Vaccine Boos...
doi: 10.1097/ICO.0000000000000199
Case Report

Herpes Zoster Stromal Keratitis After Varicella Vaccine Booster in a Pediatric Patient

Krall, Peter MD; Kubal, Anup MD

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Purpose: In this study, the case of a healthy pediatric patient who presented with herpes zoster (HZ) stromal keratitis after vaccination with live attenuated varicella vaccine (Varivax) and subsequent booster is described.

Method: This is a retrospective case review.

Results: A 6-year-old girl with no medical history presented with HZ ophthalmicus and stromal keratitis. She had received the original Varivax vaccine at 1 year of age and a booster 1 year before presentation. Topical prednisolone acetate was started with subsequent improvement in inflammation and visual acuity. However, the patient was unable to be completely tapered off the steroids because of reactivation.

Conclusions: HZ ophthalmicus with stromal keratitis is a rare but potentially damaging manifestation of the varicella zoster virus in the pediatric population. Long-term data regarding reactivation rates in the post-vaccination era are still limited. Close follow-up is needed to ensure resolution of the infiltrates, and reactivation may require long-term steroid therapy.

© 2014 by Lippincott Williams & Wilkins.


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