Skip Navigation LinksHome > August 2014 - Volume 33 - Issue 8 > Infectious Scleritis in Taiwan—A 10-Year Review in a Tertiar...
doi: 10.1097/ICO.0000000000000174
Clinical Science

Infectious Scleritis in Taiwan—A 10-Year Review in a Tertiary-Care Hospital

Ho, Yeen-Fey MD*; Yeh, Lung-Kun MD, PhD*,†; Tan, Hsin-Yuan MD*,†; Chen, Hung-Chi MD, PhD*,†; Chen, Yeong-Fong MD*,†; Lin, Hsin-Chiung MD*,†; Chen, Shin-Yi MD*,†; Hui-Kang, David Ma MD, PhD*,†; Hsiao, Ching-Hsi MD*,†

Collapse Box


Purpose: The aim of this study was to describe the clinical features of infectious scleritis with distinct inciting events and to analyze the factors associated with poor visual outcome.

Methods: We retrospectively reviewed the predisposing factors, clinical findings, isolated organisms, complications, and outcomes of patients with infectious scleritis examined between January 2003 and December 2012 at the Chang Gung Memorial Hospital, Taiwan.

Results: Forty-five (94%) of 48 patients with infectious scleritis had preceding inciting factors. Prior ocular surgery (40 eyes, 83%), especially pterygium excision (27 eyes, 57%), accounted for the majority of cases; prior accidental injury was found in 5 eyes (10%). The trauma group had a significantly shorter latency and duration of symptoms before diagnosis when compared with the surgery group. Pseudomonas aeruginosa (22 eyes, 46%) was the most commonly identified pathogen, and fungus was detected in 7 eyes (15%). Fungal infections had a longer symptom duration and smaller scleral ulcers at presentations than bacterial infections did. All patients were administered antimicrobials, and early surgical debridement (median 3 days) was performed in 38 eyes (79%). Three eyes (6%) required eyeball removal, and 10 patients (21%) had a posttreatment vision >20/200. With univariate analysis, the identified factors that were significantly associated with poor visual outcomes were visual acuity at presentation worse than 20/200 (P = 0.01), a long duration of hospitalization (P = 0.02), and eyes complicated by scleral thinning (P = 0.034).

Conclusions: Infectious scleritis associated with distinct inciting factors or different offending organisms can display divergent characteristics. Intensive antimicrobial treatment and early surgical debridement can salvage eyes.

© 2014 by Lippincott Williams & Wilkins.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.