Skip Navigation LinksHome > August 2014 - Volume 33 - Issue 8 > Combined Topical Application of a Regenerative Agent With a...
doi: 10.1097/ICO.0000000000000169
Case Report

Combined Topical Application of a Regenerative Agent With a Bandage Contact Lens for the Treatment of Persistent Epithelial Defects

Kymionis, George D. MD, PhD*,†; Liakopoulos, Dimitrios A. MD*; Grentzelos, Michael A. MD*; Diakonis, Vasilios F. MD, PhD*; Klados, Nektarios E. MD*; Tsoulnaras, Konstantinos I. MD*; Tsilimbaris, Miltiadis K. MD, PhD*; Pallikaris, Ioannis G. MD, PhD*

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Purpose: The aim of this study was to report 3 cases of persistent epithelial defects (PEDs) successfully treated with the combined topical application of a regenerative agent (RGTA; Cacicol20, OTR3, Paris, France) with a bandage contact lens (BCL).

Methods: This is a case series.

Results: Three patients suffering from a PED for 4–8 weeks and unresponsive to conventional therapy were treated with the combined application of an RGTA (Cacicol20) and a silicone hydrogel BCL. The PED healed in all patients after 4–21 days, and no side effects were noted.

Conclusions: The combination of an RGTA (Cacicol20) with a BCL seems to be an effective treatment for PED.

© 2014 by Lippincott Williams & Wilkins.


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