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Obesity and Obstructive Sleep Apnea in Patients With Keratoconus in a Turkish Population

Gencer, Baran MD; Ozgurhan, Engin Bilge MD; Kara, Selcuk MD; Tufan, Hasan Ali MD; Arikan, Sedat MD; Bozkurt, Ercument MD; Demirok, Ahmet MD

doi: 10.1097/ICO.0000000000000024
Clinical Science

Purpose: The aim of this study was to compare the frequency of occurrence of obesity and high risk of developing obstructive sleep apnea (OSA) in a keratoconus population with that of a control group.

Methods: This prospective, case-controlled multicenter study was performed on patients with keratoconus and age- and gender-matched control subjects. One hundred forty-six patients were included in each group, and the Berlin Questionnaire was used for classifying patients as having a high risk or low risk of developing OSA. The patients' demographic and clinical characteristics were compared with the Mann–Whitney U test for continuous variables and with the χ2 test for categorical variables.

Results: The keratoconus (85 male/61 female) and control (79 male/67 female) groups' median ages were 25 (8–65) and 24 (9–60) years, respectively. Of the 146 patients in each group, 11 (7.5%) patients were determined to be at a high risk of developing OSA in the keratoconus group, and 8 (5.5%) patients were determined to be at a high risk of developing OSA in the control group. There was no significant difference between the groups (P = 0.477). The keratoconus and control groups' median body mass index values were found to be within normal ranges of 23.2 and 23.4, respectively.

Conclusions: In this study, the mean body mass index value of the keratoconus group was determined to be within normal limits. In a Turkish population, the ratio of a high risk of developing OSA was not found to be significantly different between the keratoconus and control groups.

*Department of Ophthalmology, School of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey;

Beyoglu Eye Research and Training Hospital, Istanbul, Turkey; and

Department of Ophthalmology, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.

Reprints: Baran Gencer, Department of Ophthalmology, School of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey (e-mail: barangencer@gmail.com).

The authors have no funding or conflicts of interest to disclose.

Received June 17, 2013

Accepted October 02, 2013

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