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doi: 10.1097/ICO.0b013e3182a73a10
Case Report

Corneal Keloid: Report of Natural History and Outcome of Surgical Management in Two Cases

Bakhtiari, Pejman MD*; Agarwal, Daniel R. MD; Fernandez, Ana Alzaga MD; Milman, Tatyana MD; Glasgow, Ben MD*; Starr, Christopher E. MD; Aldave, Anthony J. MD*

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Purpose: To report the natural history and the outcome after the surgical management of 2 cases of corneal keloids.

Methods: Two male patients, 21 and 24 years old, with a history of corneal opacity for 5 and 17 years, respectively, with no history of an ocular trauma were studied.

Results: The first patient initially underwent a superficial keratectomy (SK), after which the corneal opacification recurred. He subsequently underwent 2 SK procedures combined with phototherapeutic keratectomy and mitomycin C, followed by a femtosecond laser–assisted deep anterior lamellar keratoplasty. The second patient underwent a bilateral SK followed by a penetrating keratoplasty in the left eye with the rapid recurrence of the lesion. The patient subsequently underwent an implantation of a Boston type 1 keratoprosthesis in the right eye, with a favorable outcome. The histopathologic features of both excised corneal specimens were consistent with the diagnosis of a corneal keloid.

Conclusions: Corneal keloids recur after SK and phototherapeutic keratectomy, indicating that keratoplasty procedures may be more effective than keratectomy procedures in their management. However, corneal keloids may recur even after a penetrating keratoplasty, in which case keratoprosthesis implantation represents a viable option for visual rehabilitation.

© 2013 by Lippincott Williams & Wilkins.


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