Purpose: To report 3 cases of keratoconic patients who had progressive corneal topographic flattening during a 2-year follow-up period.
Methods: Case series.
Results: Three patients with bilateral keratoconus, each operated for advanced keratoconus in one of their eyes, were observed for possible progression of the disorder for a period of 2 years. During the 2-year follow-up period, topographic examination showed progressive corneal flattening in the nonoperated eye. Mean keratometry decreased in all patients, whereas topography showed significant flattening at the apex of the cone. Best-spectacle-corrected visual acuity increased in one of the patients, whereas the others had stable uncorrected and best-spectacle-corrected visual acuity during the follow-up period. All patients had positive family medical history for diabetes mellitus, but none of them was diabetic.
Conclusions: This is the first report of topography-based keratoconus regression during a 2-year follow-up period.
*Vardinoyiannion Eye Institute of Crete, Department of Cornea, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece;
†Cornea and Refractive Services, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL.
Reprints: George D. Kymionis, Vardinoyiannion Eye Institute of Crete (VEIC), Faculty of Medicine, University of Crete, 71003 Heraklion, Crete, Greece (e-mail: firstname.lastname@example.org).
The authors have no funding or conflicts of interest to disclose.
Received February 14, 2013
Accepted April 12, 2013