Purpose: To develop an internationally agreed terminology for describing ocular tissue grafts to improve the accuracy and reliability of information transfer, to enhance tissue traceability, and to facilitate the gathering of comparative global activity data, including denominator data for use in biovigilance analyses.
Methods: ICCBBA, the international standards organization for terminology, coding, and labeling of blood, cells, and tissues, approached the major Eye Bank Associations to form an expert advisory group. The group met by regular conference calls to develop a standard terminology, which was released for public consultation and amended accordingly.
Results: The terminology uses broad definitions (Classes) with modifying characteristics (Attributes) to define each ocular tissue product. The terminology may be used within the ISBT 128 system to label tissue products with standardized bar codes enabling the electronic capture of critical data in the collection, processing, and distribution of tissues. Guidance on coding and labeling has also been developed.
Conclusions: The development of a standard terminology for ocular tissue marks an important step for improving traceability and reducing the risk of mistakes due to transcription errors. ISBT 128 computer codes have been assigned and may now be used to label ocular tissues. Eye banks are encouraged to adopt this standard terminology and move toward full implementation of ISBT 128 nomenclature, coding, and labeling.
*School of Clinical Sciences, University of Bristol, Bristol, United Kingdom;
†ICCBBA, Chatham, United Kingdom;
‡Lions VisionGift, Portland, OR;
§The Eye-Bank for Sight Restoration, Inc, New York, NY;
¶Eye Bank Association of America, Washington, DC;
‖ICCBBA, Redlands, CA;
**Ramayama International Eye Bank, L V Prasad Eye Institute, Hyderabad, India;
††Queensland Eye Institute, Brisbane, Australia;
‡‡Department of Ophthalmology and Vision Science, University of California Davis Eye Center, Davis, CA;
§§New Zealand National Eye Bank, Auckland, New Zealand;
¶¶Veneto Eye Bank Foundation, Venice, Italy; and
‖‖Singapore National Eye Centre, Singapore, Singapore.
Correspondence and Reprints: Pat Distler, ICCBBA, PO Box 11309, San Bernadino, CA 92423-1309 (e-mail: firstname.lastname@example.org).
Supported by ICCBBA, an international not-for-profit organization responsible for the ISBT 128 information standard.
P. Ashford is a consultant to ICCBBA and P. Distler is employed by ICCBBA. W.J. Armitage received travel funding from ICCBBA. The remaining authors have no conflicts of interest.
Received December 20, 2012
Accepted January 09, 2013