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Corneal Cross-Linking in Patients With Radial Keratotomy: Short-term Follow-up

Fuentes-Páez, Graciana MD; Castanera, Fernando MD; Salazar-Martinez, Rocio Gómez de DDO; Salas, Jose Fernández DDO; Izquierdo, Estefania BSN; Pinalla, Beatriz BSN

doi: 10.1097/ICO.0b013e31821f28bb
Clinical Science

Purpose: To record visual and refractive data in eyes with previous radial keratotomy (RK) and corneal instability undergoing corneal cross-linking (CXL).

Methods: Case series of eyes with RK and refractive instability undergoing CXL with riboflavin and UV-A radiation. The following variables were recorded before 3 and 6 months after CXL: sphere, spherical equivalent (SE), uncorrected visual acuity (UCVA), best spectacle–corrected visual acuity (BSCVA), topographic astigmatism, mean topographic K (Km), pachymetry, and Q values.

Results: Seven eyes of 4 patients with pre-CXL variables included mean sphere [−0.7 ± 3.2 diopters (D)], astigmatism (2.5 ± 1.17 D), SE (−2.1 ± 3.1 D), UCVA (0.3 ± 2.0), BSCVA (0.63 ± 0.36), Km (38.75 ± 5.74 D), pachymetry (522 ± 36.8 μm), and Q (1.73 ± 1.34). Three months after CXL, mean sphere was +1.0 ± 3.0 D (P = 0.00); astigmatism, 2.5 ± 1.2 D (P = 0.95); SE, 0.3 ± 2.2 D (P = 0.008); UCVA, 0.41 ± 2.7 (P = 0.22); BSCVA, 0.80 ± 0.27 (P = 0.14); Km, 37.5 ± 5.7 D (P = 0.3); pachymetry, 491 ± 33.74 μm (P = 0.00); and Q, 2.27 ± 1.8 (P = 0.22). Six months after CXL, mean sphere was 0.53 ± 3.5 D (P = 0.00); astigmatism, 1.62 ± 1.76 D (P = 0.13); SE, 0.52 ± 2.9 D (P = 0.023); UCVA, 0.60 ± 2.0 (P = 0.018); BSCVA, 0.9 ± 0.15 (P = 0.03); Km, 38.3 ± 4.10 D (P = 0.64); and Q, 1.7 ± 0.78 (P = 0.80).

Conclusions: Short-term follow-up of RK patients treated with CXL showed clinical and statistically significant improvement.

From the Clinica TACIR-Centro Medico TEKNON, Barcelona, Spain.

Received for publication October 24, 2010; revision received April 7, 2011; accepted April 10, 2011.

The authors state that they have no financial or conflicts of interest to disclose.

Reprints: Graciana Fuentes-Páez, Clinica TACIR-Centro Médico TEKNON, Calle Vilana 12, Consultorios 118-119, Barcelona 08033, Spain (e-mail: fupaez@yahoo.com).

© 2012 Lippincott Williams & Wilkins, Inc.