Institutional members access full text with Ovid®

Share this article on:

Comparison of Corneal Thickness and Haze in DSAEK and Penetrating Keratoplasty

Uchino, Yuichi MD; Shimmura, Shigeto MD; Yamaguchi, Takefumi MD; Kawakita, Tetsuya MD; Matsumoto, Yukihiro MD; Negishi, Kazuno MD; Tsubota, Kazuo MD

doi: 10.1097/ICO.0b013e3181eeafd6
Clinical Science

Purpose: To compare corneal thickness and haze in Descemet stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PK).

Methods: This study included 30 consecutive patients undergoing DSAEK (18 patients) and PK (12 patients). Central corneal thickness and corneal haze were analyzed longitudinally by Pentacam (Oculus, Wetzlar, Germany) at 2 weeks, 1 month, and 3 months after grafting.

Results: The mean age of patients in the DSAEK group was 71.42 ± 9.91 years (range, 55-85 years) and in the PK group was 60.58 ± 16.58 years (range, 31-81 years). Two weeks, 1 month, and 3 months after surgery, the cornea was significantly thicker in the DSAEK group compared with the PK group (P < 0.01). Two weeks, 1 month, and 3 months after the operation, the cornea had significantly more haze in the DSAEK group compared with the PK group (P < 0.05). Haze in the DSAEK group was mainly observed in the subepithelial stroma.

Conclusions: DSAEK grafts were significantly thicker with increased haze for up to 3 months after surgery. Scheimpflug system is available for quantifying not only corneal thickness but also corneal haze after various keratoplasty procedures.

From the Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

Received for publication September 17, 2009; revision received June 4, 2010; accepted June 18, 2010.

Reprints: Shigeto Shimmura, Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8285, Japan (e-mail: shige@sc.itc.keio.ac.jp).

© 2011 Lippincott Williams & Wilkins, Inc.