Skip Navigation LinksHome > May 2010 - Volume 29 - Issue 5 > Mitomycin C Does Not Inhibit Exacerbation of Granular Cornea...
doi: 10.1097/ICO.0b013e3181c3258a
Clinical Science

Mitomycin C Does Not Inhibit Exacerbation of Granular Corneal Dystrophy Type II Induced by Refractive Surface Ablation

Ha, Byoung Jin MD*; Kim, Tae-im MD†‡; Choi, Seung-il PhD†‡; Stulting, R Doyle MD, PhD§; Lee, Dong Ho MD¶ ; Cho, Hyun-Soo PhD‖; Kim, Eung Kweon MD, PhD†‡

Collapse Box


Purpose: To evaluate the effect of mitomycin C (MMC) on the exacerbation of corneal opacity that occurs in patients with granular corneal dystrophy type II (GCD II) after refractive corneal surface ablation.

Methods: Ten eyes of patients with GCD II who underwent refractive corneal surface ablation with MMC were compared with 10 eyes that were not treated with MMC. Best spectacle-corrected visual acuity, the degree of corneal opacity, and contrast sensitivity were evaluated at least 3 years after surgery. Corneal opacities were quantified using Pentacam densitometry maps.

Results: No measured between-group value showed a statistically significant difference.

Conclusion: Simultaneous application of MMC does not prevent exacerbation of GCD II after refractive corneal surface ablation.

© 2010 Lippincott Williams & Wilkins, Inc.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.