Cornea

Skip Navigation LinksHome > May 2010 - Volume 29 - Issue 5 > Fibrin Adhesive Is Better Than Sutures in Pterygium Surgery
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Cornea:
doi: 10.1097/ICO.0b013e3181c29696
Clinical Science

Fibrin Adhesive Is Better Than Sutures in Pterygium Surgery

Ratnalingam, Vanitha MSurg (Ophthal); Keat Eu, Andrew Lim MMed (Ophthal); Ng, Gim Leong MMed (Ophthal); Taharin, Rohana MSurg (Ophthal); John, Elizabeth DO

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Abstract

Purpose: To evaluate the recurrence rate, surgical time, and postoperative pain between conjunctival autografting with sutures and with fibrin adhesive in pterygium surgery.

Methods: A prospective, randomized, double-blind, clinical trial on the benefits of using fibrin adhesive in place of sutures in pterygium surgery. One hundred seventy-five eyes with primary pterygium were randomized to undergo pterygium surgery with conjunctival autograft transplantation using either fibrin adhesive or sutures. One hundred thirty-seven eyes of 113 patients that were operated on by a single surgeon (V.R.) completed the 1-year follow-up. Sixty-eight eyes were operated with fibrin adhesive and 69 eyes with sutures. Patients were followed up at 1 day, 1 week, 1 month, 6 months, and 1 year after surgery. Pterygium recurrence and postoperative pain was graded by an independent observer (A.L.) masked to the method of treatment. Surgical time was measured with a stopwatch.

Results: All patients were followed up for 1 year. There were 3 recurrences (4.41%) in the fibrin adhesive group and 11 recurrences (15.9%) in the suture group. The mean duration required to complete surgery in the fibrin adhesive group was 16.93 ± 2.85 minutes, whereas that of the suture group was 29.84 ± 5.65 minutes, which was statistically significant (P < 0.001). The immediate postoperative pain score and week 1 postoperative pain score were significantly lower in the fibrin adhesive group (P < 0.05). No major complications were observed in either group.

Conclusion: The use of fibrin adhesive in primary pterygium surgery with conjunctival autografts reduces the recurrence rate, surgical time, and postoperative pain when compared with sutures.

© 2010 Lippincott Williams & Wilkins, Inc.

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