Purpose: To describe the use of soft contact lenses (CL) to reduce the epithelial opacities of Lisch epithelial corneal dystrophy (LECD). First presentation of confocal microscopy in LECD.
Methods: Two unrelated female patients with LECD demonstrated a central gray opacity with distinct visual impairment. The first patient wore a daily hydroxyethlmethacrylate (HEMA) CL for 3 months and the second, a daily silicone hydrogel CL for 1 month. Pre-CL and post-CL appearances of the cornea were photodocumented at the slit lamp. Additionally, in the second patient, a confocal microscopic evaluation of LECD was performed.
Results: In both patients, the wearing of CL resulted in a distinct reduction of central corneal opacification with a visual improvement. Discontinued wearing of CL induced again a progression of opacity. The confocal microscopy disclosed the typical intracytoplasmatic vacuolization of the involved epithelial cells.
Conclusions: Wearing CL for a longer duration causes a significant regression of corneal opacities in LECD. The etiology of this phenomenon is interpreted as a CL-induced thinning of corneal epithelium and reduction of epithelial layers.
From the *Department of Ophthalmology, Klinikum Hanau, Hanau, Germany; and †Department of Ophthalmology, Johannes-Gutenberg-University Mainz, Mainz, Germany.
Received for publication November 9, 2008; revision received March 20, 2009; accepted April 16, 2009.
The authors state that they do not have any proprietary interest in this study.
Reprints: Walter Lisch, MD, Department of Ophthalmology, Klinikum Hanau, Leimenstrasse 20, D-63450, Hanau, Germany (e-mail: Lisch.Hanau@t-online.de).