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Cornea:
doi: 10.1097/ICO.0b013e31817c41e3
Case Report

Combined Use of Superficial Keratectomy and Subconjunctival Bevacizumab Injection for Corneal Neovascularization

Qian, Cynthia Xin-ya MD*; Bahar, Irit MD†; Levinger, Eliya MD†; Rootman, David MD, FRCSC†

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Abstract

Purpose: To report the effect of superficial keratectomy combined with subconjunctival bevacizumab injection in 2 cases of corneal neovascularization (NV).

Methods: An interventional case series was undertaken on 2 patients with corneal NV: 1 due to sclerokeratitis secondary to rheumatoid arthritis and the other due to Terrien marginal degeneration. Both patients underwent superficial keratectomy combined with subconjunctival bevacizumab injection (2.5 mg/0.1 mL).

Results: Corneal NV regressed with the surgical removal and showed no signs of recurrence after 3 months of follow-up. Both patients reported dramatic subjective improvement in their vision within 1-2 weeks. Best corrected visual acuity improved in 1 patient.

Conclusion: The combination of superficial keratectomy with subconjunctival injection of bevacizumab may offer a new strategy for the treatment of superficial corneal NV.

© 2008 Lippincott Williams & Wilkins, Inc.

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