Cornea

Skip Navigation LinksHome > July 2004 - Volume 23 - Issue 5 > Concomitant Keratoconus and Macular Corneal Dystrophy
Cornea:
Case Reports

Concomitant Keratoconus and Macular Corneal Dystrophy

Javadi, Mohammad-Ali MD*; Rafee’i, Alireza Baradaran MD*; Kamalian, Nasser MD†; Karimian, Farid MD*; Ja’farinasab, Mohammad-Reza MD*; Yazdani, Shahin MD‡

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Abstract

Objective: To report the concomitant presentation of keratoconus and macular corneal dystrophy in two cases.

Methods: Two siblings with concomitant keratoconus and macular corneal dystrophy are presented. Complete ophthalmologic examination and computerized videokeratography were performed in both patients. Case 1 underwent penetrating keratoplasty in both eyes sequentially; histopathologic examination of excised corneal buttons with special stains was performed. Case 2 was observed.

Results: Both patients manifested typical signs and topographic evidence of keratoconus associated with macular dystrophy. Histopathologic studies in case 1 confirmed the same clinical diagnosis.

Conclusion: To our knowledge, this is the first report of such a concurrence in the English literature and could lead to further studies on the possible pathophysiologic or genetic link between these 2 entities.

© 2004 Lippincott Williams & Wilkins, Inc.

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