Brown-McLean Syndrome Occurring in a Corneal Graft.Sugar, Alan M.D.Cornea: July 1997 Original Article: PDF Only Abstract Purpose. To present a case of Brown-McLean syndrome occurring in a transplanted cornea. Methods. Retrospective case report. Results. A patient had penetrating keratoplasty performed for bullous keratopathy 6 years after intracapsular cataract extraction in the right eye. She developed atypical Brown-McLean syndrome in the left eye 6 years after extracapsular cataract extraction with pupil-support intraocular lens (IOL) insertion and later IOL removal. The clear corneal graft in the right eye developed peripheral stromal and epithelial edema with pigmentation of the endothelium, consistent with Brown-McLean syndrome 9 years after keratoplasty. Conclusion. Brown-McLean syndrome can occur in a grafted cornea, although the features may differ from those seen in ungrafted corneas (C) Lippincott-Raven Publishers.