Corneal Perforation in a Patient with Cockayne's Syndrome.Yamaguchi, Katsuhiro M.D.; Okabe, Hitoshi M.D.; Tamai, Makoto M.D.Cornea: January 1991 CASE REPORTS: PDF Only Abstract : A 10-year-old boy with Cockayne's syndrome had an aseptic perforation centered in a corneal opacity of the right eye. Exposure keratitis, which was caused by anhidrosis, loss of blinking, and lack of Bell's phenomenon, was considered responsible for this condition. A therapeutic soft contact lens was applied to heal the corneal wound. (C) Lippincott-Raven Publishers.