Video demonstrates laughter-induced cataplexy in a child. This child has the hypocretin gene defect leading to narcolepsy with cataplexy. He is dancing and playing, and children are laughing in the background, which leads him to become excited and lose muscle tone in the legs. While the condition is exclusively genetically based in animals, it is not the case in humans, and was not the case in this patient.
Soňa Nevšímalová, MD, DSc
CONTINUUM: Lifelong Learning in Neurology. 19(1, Sleep Disorders):67-85, February 2013