Progressive Supranuclear Palsy–Parkinsonism
A 58-year-old woman with an early clinical diagnosis of Parkinson disease who progressed to a progressive supranuclear palsy phenotype between 6 and 8 years after symptom onset (both time points shown in the video). Later development of oculomotor impairment and blepharospasm with apraxia of eyelid opening were clues regarding the revised diagnosis.
David R. Williams, MBBS, PhD, FRACP
CONTINUUM: Lifelong Learning in Neurology. 19(5, Movement Disorders):1189-1212, October 2013