CONTINUUM: Lifelong Learning in Neurology:
doi: 10.1212/01.CON.0000446109.20539.68
Review Articles

Genetic Stroke Syndromes

Barrett, Kevin M. MD, MSc; Meschia, James F. MD

Collapse Box


Purpose of Review:: This review describes the clinical and radiographic features, genetic determinants, and treatment options for the most well-characterized monogenic disorders associated with stroke.

Recent Findings:: Stroke is a phenotype of many clinically important inherited disorders. Recognition of the clinical manifestations of genetic disorders associated with stroke is important for accurate diagnosis and prognosis. Genetic studies have led to the discovery of specific mutations associated with the clinical phenotypes of many inherited stroke syndromes.

Summary:: Several inherited causes of stroke have established and effective therapies, further underscoring the importance of timely diagnosis.

© 2014 American Academy of Neurology


Article Tools


Article Level Metrics

You currently do not have access to this article.

You may need to:

Note: If your society membership provides for full-access to this article, you may need to login on your society’s web site first.